Obagi CLENZIdermŪ M.D. Systems are the only prescription-strength acne treatments that contain a patented, solubilized form of 5% benzoyl peroxide (BPO) to penetrate deep into the follicle and treat acne where it starts. Exclusive penetrating technology that delivers BPO to the root of acne. Clinically significant lesion reduction in 2 weeks, compared to the leading topical prescription BPO/clindamycin combination. Availability of two distinct, prescription-strength formulations for a broad range of skin types.